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CYTOMEL® liothyronine sodium Dosage and Administration US

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CYTOMEL® liothyronine sodium Dosage and Administration US

Closely monitor coagulation tests to permit appropriate and timely dosage adjustments. Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various gastrointestinal symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness and wheezing. CYTOMEL has a rapid onset of action and residual effects of the other thyroid preparation may persist for the first several weeks after initiating CYTOMEL therapy. Symptoms of low thyroid hormone levels include tiredness, muscle aches, constipation, dry skin, weight gain, slow heartbeat, or sensitivity to cold.

In pediatric patients with hypothyroidism, assess the adequacy of replacement therapy by measuring serum TSH and T3 levels. ​In adult patients with primary hypothyroidism, monitor serum TSH periodically after initiation of the therapy https://y-hoc.com/steroid/nandrolone-how-to-buy/ or any change in dose. To check the immediate response to therapy before the TSH has had a chance to respond or if your patient’s status needs to be assessed prior to that point, measurement of total T3 would be most appropriate.

Thyroid hormones do not easily cross the placenta and, therefore, are safe for pregnant women to take. Consider changes in TBG concentration when interpreting T4 and T3 values. Measure and evaluate unbound (free) hormone in this circumstance. Pregnancy, infectious hepatitis, estrogens, estrogen-containing oral contraceptives, and acute intermittent porphyria increase TBG concentrations. Nephrosis, severe hypoproteinemia, severe liver disease, acromegaly, androgens and corticosteroids decrease TBG concentration. Familial hyper- or hypo-thyroxine binding globulinemias have been described, with the incidence of TBG deficiency approximating 1 in 9000.

Related/similar drugs

Since thyroid hormone occurs naturally in the body, almost anyone can take Cytomel. Along with its needed effects, liothyronine (the active ingredient contained in Cytomel) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. When given as part of a thyroid suppression test, you will need to take liothyronine for several days in a row in preparation for the test. When given as part of a thyroid suppression test, you will need to take this medicine for several days in a row in preparation for the test. If symptoms occur, they usually occur because there are toxic (too high) levels of thyroid hormone (hyperthyroidism).

Pregnancy & Lactation

​Serum TSH is not a reliable measure of CYTOMEL dose adequacy in patients with secondary or tertiary hypothyroidism and should not be used to monitor therapy. Use the serum T3 level to monitor adequacy of therapy in this patient population. ​The recommended starting dosage is 25 mcg orally once daily. Increase the dose by 25 mcg daily every 1 or 2 weeks, if needed. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Recommended Dosage for Thyroid Suppression Test

Monitor patients receiving concomitant CYTOMEL and sympathomimetic agents for signs and symptoms of coronary insufficiency. If cardiovascular symptoms develop or worsen, reduce or withhold the CYTOMEL dose for one week and restart at a lower dose. CYTOMEL increases the response to oral anticoagulant therapy. Therefore, a decrease in the dose of anticoagulant may be warranted with correction of the hypothyroid state or when the CYTOMEL dose is increased.